diff --git a/Models/ReactionTest.cs b/Models/ReactionTest.cs
--- a/Models/ReactionTest.cs
+++ b/Models/ReactionTest.cs
@@ -279,6 +279,7 @@ namespace DesertPaintCodex.Models
         {
             Reaction = new Reaction(0, 0, 0);
             State = TestState.GoodResult;
+            SaveReaction();
         }
 
         public void ClearReaction()
@@ -291,11 +292,15 @@ namespace DesertPaintCodex.Models
             {
                 profile.Save();
             }
+
+            BufferReagentFirst = null;
+            BufferReagentLast = null;
             
             Reaction = null;
             BadReaction = null;
             Clipped = ClipType.None;
             State = TestState.Untested;
+            
             UpdateRecipe();
         }
 
diff --git a/ViewModels/ExperimentLogViewModel.cs b/ViewModels/ExperimentLogViewModel.cs
--- a/ViewModels/ExperimentLogViewModel.cs
+++ b/ViewModels/ExperimentLogViewModel.cs
@@ -61,6 +61,7 @@ namespace DesertPaintCodex.ViewModels
             TestView.SaveReaction.Subscribe(_ => OnSaveReaction());
             TestView.ClearReaction.Subscribe(_ => OnClearReaction());
             TestView.FinalizeTestResults.Subscribe(_ => OnReactionResults());
+            TestView.MarkInert.Subscribe(_ => OnSaveReaction());
         }
 
         private ReactionTest GetSelectedReactionTest()
diff --git a/ViewModels/ReactionTestViewModel.cs b/ViewModels/ReactionTestViewModel.cs
--- a/ViewModels/ReactionTestViewModel.cs
+++ b/ViewModels/ReactionTestViewModel.cs
@@ -46,6 +46,7 @@ namespace DesertPaintCodex.ViewModels
             ShowScreenSettingsDialog = new Interaction<ScreenSettingsViewModel, Unit>();
             SaveReaction = ReactiveCommand.Create(() => ReactionTest.SaveReaction());
             ClearReaction = ReactiveCommand.Create(() => ReactionTest.ClearReaction());
+            MarkInert = ReactiveCommand.Create(() => ReactionTest.MarkInert());
             FinalizeTestResults = ReactiveCommand.Create(Test);
         }
 
@@ -109,11 +110,6 @@ namespace DesertPaintCodex.ViewModels
             }
         }
 
-        public void MarkInert()
-        {
-            ReactionTest.MarkInert();
-        }
-
         public void CancelScan()
         {
             ReactionTest.CancelScan();
@@ -148,6 +144,9 @@ namespace DesertPaintCodex.ViewModels
 
         public ReactiveCommand<Unit, Unit> ClearReaction { get; }
         public ReactiveCommand<Unit, Unit> SaveReaction { get; }
+        
+        public ReactiveCommand<Unit, Unit> MarkInert { get; }
+        
         public ReactiveCommand<Unit, Unit> FinalizeTestResults { get; }
     }
 }
\ No newline at end of file